A device for delivering a medicament to a patient in need thereof includes: (a) an injector including a first end configured to remain outside a nasal passage of the patient and a second end configured for entry into the nasal passage of the patient, wherein the injector is moveable between a storage position and an engaging position; and (b) an introducer configured for engagement with a nostril of the patient, wherein the introducer includes a passageway configured for slidably receiving the injector, and wherein the introducer includes a curvature along a portion thereof adjacent to the passageway. Methods for ameliorating pain in a patient include (a) introducing the injector through the nasal passage of the patient into a region substantially medial and/or posterior and/or inferior to a sphenopalatine ganglion of the patient; and (b) delivering a medicament from the injector superiorly and/or laterally and/or anteriorly towards the sphenopalatine ganglion.