发明申请
US20110159508A1 GFATS as Modifiers of the P53 Pathway and Methods of Use
审中-公开
GFATS作为P53途径的修饰物和使用方法
- 专利标题： GFATS as Modifiers of the P53 Pathway and Methods of Use
- 专利标题（中）： GFATS作为P53途径的修饰物和使用方法
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申请号： US12900340申请日： 2010-10-07
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公开(公告)号： US20110159508A1公开(公告)日： 2011-06-30
- 发明人: Lori Friedman , Gregory D. Plowman , Marcia Belvin , Helen Francis-Lang , Danxi Li , Roel P. Funke
- 申请人： Lori Friedman , Gregory D. Plowman , Marcia Belvin , Helen Francis-Lang , Danxi Li , Roel P. Funke
- 申请人地址： US CA South San Francisco
- 专利权人： EXELIXIS, INC.
- 当前专利权人： EXELIXIS, INC.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12Q1/52 ; G01N33/574
摘要：
Human GFAT genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of GFAT are provided.
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