发明申请
US20110160229A1 AHCY HYDROLASE INHIBITORS FOR TREATMENT OF HYPER HOMOCYSTEINEMIA
失效
AHCY水解酶抑制剂治疗高血糖综合征
- 专利标题： AHCY HYDROLASE INHIBITORS FOR TREATMENT OF HYPER HOMOCYSTEINEMIA
- 专利标题（中）： AHCY水解酶抑制剂治疗高血糖综合征
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申请号： US13060775申请日： 2009-08-31
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公开(公告)号： US20110160229A1公开(公告)日： 2011-06-30
- 发明人: Antonella Converso , Timothy J. Hartingh , Mark E. Fraley
- 申请人： Antonella Converso , Timothy J. Hartingh , Mark E. Fraley
- 国际申请： PCT/US2009/055501 WO 20090831
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; C07D471/04 ; C07D473/34 ; A61K31/437 ; A61P25/28 ; A61P9/00 ; A61P25/00 ; A61P19/10 ; A61P25/16 ; A61P25/18 ; A61P9/12
摘要：
The present invention is directed to AHCY inhibitors of formula (I): which are useful in the treatment of diseases characterized by high homocysteine levels, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases characterized by high homocysteine levels.
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