发明申请
- 专利标题: 5-LIPOXYGENASE-ACTIVATING PROTEIN INHIBITOR
- 专利标题(中): 5-LIPOXYGENASE-活化蛋白抑制剂
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申请号: US12993319申请日: 2009-05-22
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公开(公告)号: US20110160249A1公开(公告)日: 2011-06-30
- 发明人: Kevin Murray Schaab , Christopher David King , Nicholas Simon Stock
- 申请人: Kevin Murray Schaab , Christopher David King , Nicholas Simon Stock
- 国际申请: PCT/US2009/044945 WO 20090522
- 主分类号: A61K31/444
- IPC分类号: A61K31/444 ; C07D401/14 ; A61P11/06 ; A61P11/00 ; A61P9/00
摘要:
A pharmaceutically acceptable salt comprising 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxy-pyridin-3-yl)-benzyl]-5-(5-methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionate as the anion and a cation selected from Na+, K+, Li+, Ca2+, NH4+, the protonated form of dicyclohexylamine, the protonated form of N-methyl-D-glucamine, the protonated form of tris(hydroxymethyl)methylamine, the protonated form of arginine, and the protonated form of lysine is disclosed, along with formulations and methods of using the same.
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