发明申请
US20110165223A1 Antitumor Immunization by Liposomal Delivery of Vaccine to the Spleen
审中-公开
通过脂质体向脾输送疫苗的抗肿瘤免疫
- 专利标题： Antitumor Immunization by Liposomal Delivery of Vaccine to the Spleen
- 专利标题（中）： 通过脂质体向脾输送疫苗的抗肿瘤免疫
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申请号： US12811620申请日： 2009-01-02
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公开(公告)号： US20110165223A1公开(公告)日： 2011-07-07
- 发明人: George Sgouros , Hong Song , Mohana Lingappa
- 申请人： George Sgouros , Hong Song , Mohana Lingappa
- 申请人地址： US MD Baltimore
- 专利权人： THE JOHNS HOPKINS UNIVERSITY
- 当前专利权人： THE JOHNS HOPKINS UNIVERSITY
- 当前专利权人地址： US MD Baltimore
- 国际申请： PCT/US09/30039 WO 20090102
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K39/00 ; A61K39/12 ; A61K47/46 ; A61P35/00 ; A61P37/04
摘要：
The present invention relates to methods for preventing, reducing or treating a variety of conditions, including cancer, and vaccines, compositions and liposomes used to elicit or amplify an immune response specific to the condition by delivering to the spleen of an individual a pegylated liposome construct having a diameter of greater than about 300 nm and including a therapeutic agent and an adjuvant for eliciting or amplifying the immune response.
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