发明申请
US20110166041A1 Diagnosis/Therapeutic Strategy For Gynecological Cancer by Utilizing Micro-RNA as Biomarker
审中-公开
通过利用微RNA作为生物标志物进行妇科癌症诊断/治疗策略
- 专利标题: Diagnosis/Therapeutic Strategy For Gynecological Cancer by Utilizing Micro-RNA as Biomarker
- 专利标题(中): 通过利用微RNA作为生物标志物进行妇科癌症诊断/治疗策略
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申请号: US12999124申请日: 2009-06-25
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公开(公告)号: US20110166041A1公开(公告)日: 2011-07-07
- 发明人: Takeru Zama , Akira Hirasawa , Koichiro Saito , Tomoko Akahane
- 申请人: Takeru Zama , Akira Hirasawa , Koichiro Saito , Tomoko Akahane
- 申请人地址: JP Tokyo
- 专利权人: KEIO UNIVERSITY
- 当前专利权人: KEIO UNIVERSITY
- 当前专利权人地址: JP Tokyo
- 优先权: JP2008-168723 20080627; JP2008-310487 20081205
- 国际申请: PCT/JP2009/002924 WO 20090625
- 主分类号: C40B40/06
- IPC分类号: C40B40/06 ; C12Q1/68
摘要:
Disclosed are: a method for using a particular microRNA as a biomarker for gynecological cancer; a method for the determination of gynecological cancer; a kit for the determination of gynecological cancer, and the like. The present invention is characterized in that at least one microRNA selected from the group of microRNAs consisting of miR-592, miR-629*, miR-517a, miR-205, miR-184, miR-509-5p, miR-135a*, miR-137, miR-602, miR-186*, miR-181a-2*, miR-193b*, miR-377*, miR-449b, miR-449a, miR-369-3p, miR-323-3p, miR-329, miR-299-5p, miR-34b, miR-411, miR-34c-5p, miR-376b, miR-885-5p, miR-337-3p, miR-337-5p, miR-127-3p, miR-138, miR-203, miR-488, miR-489, miR-643, miR-888, miR-424, miR-432, miR-433, miR-450a, miR-503, miR-542-3p, miR-542-5p and miR-584 is used as a biomarker for gynecological cancer.
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