发明申请
US20110166191A1 3-(2-amino-ethyl)-5-(3-cyclohexyl-propylidene)-thiazolidine-2,4-dione and its derivatives as multiple signaling pathway inhibitors and for the treatment of cancer
审中-公开
3-（2-氨基 - 乙基）-5-（3-环己基 - 亚丙基） - 噻唑烷-2,4-二酮及其衍生物作为多重信号通路抑制剂和治疗癌症
- 专利标题： 3-(2-amino-ethyl)-5-(3-cyclohexyl-propylidene)-thiazolidine-2,4-dione and its derivatives as multiple signaling pathway inhibitors and for the treatment of cancer
- 专利标题（中）： 3-（2-氨基 - 乙基）-5-（3-环己基 - 亚丙基） - 噻唑烷-2,4-二酮及其衍生物作为多重信号通路抑制剂和治疗癌症
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申请号： US12984825申请日： 2011-01-05
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公开(公告)号： US20110166191A1公开(公告)日： 2011-07-07
- 发明人: Shijun Zhang , Tai Liang Guo
- 申请人： Shijun Zhang , Tai Liang Guo
- 主分类号： A61K31/426
- IPC分类号： A61K31/426 ; C07D277/34 ; A61P35/00 ; C12N5/02 ; C12N9/99
摘要：
3-(2-amino-ethyl)-5-(3-cyclohexyl-propylidene)-thiazolidine-2,4-dione and derivatives thereof are provided for use as dual inhibitors of the Raf/MEK/ERK and PI3K/Akt pathways and for use in the treatment of cancer.
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