发明申请
- 专利标题： Methods and Compositions for Modulating Angiogenesis
- 专利标题（中）： 调节血管生成的方法和组合
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申请号： US13001604申请日： 2009-07-01
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公开(公告)号： US20110172293A1公开(公告)日： 2011-07-14
- 发明人: Jason E. Fish , Deepak Srivastava
- 申请人： Jason E. Fish , Deepak Srivastava
- 国际申请： PCT/US09/49438 WO 20090701
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; C07H21/04 ; C12N15/63 ; A61P35/00
摘要：
The present invention provides compositions comprising antisense nucleic acids that reduce miR-126 levels in an endothelial cell. The present invention provides compositions comprising a target protector nucleic acid. The present invention provides methods of modulating angiogenesis in an individual, the methods generally involving administering to the individual an effective amount of an agent that increases or that decreases the level of miR-126 in endothelial cells of the individual.
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