发明申请
US20110180430A1 ADJUVANTED INFLUENZA VACCINES INCLUDING CYTOKINE-INDUCING AGENTS
审中-公开
受侵染的流感病毒包括细胞因子诱导剂
- 专利标题: ADJUVANTED INFLUENZA VACCINES INCLUDING CYTOKINE-INDUCING AGENTS
- 专利标题(中): 受侵染的流感病毒包括细胞因子诱导剂
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申请号: US12092285申请日: 2006-11-06
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公开(公告)号: US20110180430A1公开(公告)日: 2011-07-28
- 发明人: Rino Rappuoli , Derek O'Hagan , Giuseppe Del Giudice
- 申请人: Rino Rappuoli , Derek O'Hagan , Giuseppe Del Giudice
- 申请人地址: IT IT Siena
- 专利权人: NOVARTIS VACCINES AND DIAGNOSTICS SRL
- 当前专利权人: NOVARTIS VACCINES AND DIAGNOSTICS SRL
- 当前专利权人地址: IT IT Siena
- 国际申请: PCT/GB06/04131 WO 20061106
- 主分类号: B65D71/00
- IPC分类号: B65D71/00 ; A61K39/145 ; A61K39/385 ; A61P31/16 ; A61P31/04 ; A61P37/04
摘要:
While oil-in-water emulsions are excellent adjuvants for influenza vaccines, their efficacy can be improved by additionally including other immunostimulating agent(s) to improve cytokine responses, such as γ-interferon response. Thus, a vaccine comprises (i) an influenza virus antigen; (ii) an oil-in-water emulsion adjuvant; and (iii) a cytokine-inducing agent.
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