发明申请
- 专利标题: Macrocyclic Prodrug Compounds Useful as Therapeutics
- 专利标题(中): 用作治疗剂的大环前药化合物
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申请号: US12861806申请日: 2010-08-23
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公开(公告)号: US20110190237A1公开(公告)日: 2011-08-04
- 发明人: James Heck , Nicolas Winssinger , John C. Chabala , Sofia Barluenga , Ruihong Chen , Allan Rubenstein , Jin-Chen Yu
- 申请人: James Heck , Nicolas Winssinger , John C. Chabala , Sofia Barluenga , Ruihong Chen , Allan Rubenstein , Jin-Chen Yu
- 申请人地址: US NY New York FR Strasbourg
- 专利权人: NEXGENIX PHARMACEUTICALS,UNIVERSITE DE STRASBOURG
- 当前专利权人: NEXGENIX PHARMACEUTICALS,UNIVERSITE DE STRASBOURG
- 当前专利权人地址: US NY New York FR Strasbourg
- 主分类号: A61K31/675
- IPC分类号: A61K31/675 ; C07F9/58 ; C07F9/59 ; A61P9/00 ; A61P29/00 ; A61P35/00 ; A61P25/00 ; A61P11/06 ; C12N5/09
摘要:
The present invention includes macrocyclic prodrug compounds, pharmaceutical compositions containing them. The present invention also includes use of these compounds in the treatment of various diseases including an autoimmune disease, an inflammatory disease, a neurological or neurodegenerative disease, cancer, a cardiovascular disease, allergy, asthma, a hormone-related disease, and tumors or symptoms resulting from neurofibromatosis.
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