发明申请
US20110190248A1 CYCLOHEXYLOXY SUBSTITUTED HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM
有权
CYCLOHEXYLOXY取代的杂环化合物,含有这些化合物的药物组合物及其制备方法
- 专利标题: CYCLOHEXYLOXY SUBSTITUTED HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM
- 专利标题(中): CYCLOHEXYLOXY取代的杂环化合物,含有这些化合物的药物组合物及其制备方法
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申请号: US13057872申请日: 2009-07-23
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公开(公告)号: US20110190248A1公开(公告)日: 2011-08-04
- 发明人: Frank Himmelsbach , Birgit Jung , Ralf Lotz
- 申请人: Frank Himmelsbach , Birgit Jung , Ralf Lotz
- 申请人地址: DE Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim am Rhein
- 优先权: EP08104995.9 20080808
- 国际申请: PCT/EP2009/059510 WO 20090723
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; A61K31/56 ; C07D403/12 ; A61P29/00 ; A61P37/08 ; A61P11/00 ; A61P11/06 ; A61P11/14 ; A61P35/00
摘要:
The present invention relates to cyclohexyloxy-substituted heterocycles of general formula (I) the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for the treatment of diseases, particularly tumoral diseases as well as benign prostatic hyperplasia (BPH), diseases of the lungs and airways and the preparation thereof.
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