发明申请
- 专利标题： PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF
- 专利标题（中）： 外周血糖受体拮抗剂及其用途
-
申请号： US12593619申请日： 2008-03-28
-
公开(公告)号： US20110190331A1公开(公告)日： 2011-08-04
- 发明人: Alfred A. Avey , Appavu Chandrasekaren , Harold D. Doshan , Julio Perez , Yakov Rotshteyn
- 申请人： Alfred A. Avey , Appavu Chandrasekaren , Harold D. Doshan , Julio Perez , Yakov Rotshteyn
- 国际申请： PCT/US2008/004109 WO 20080328
- 主分类号： A61K31/485
- IPC分类号： A61K31/485 ; C07D489/04 ; A61P25/04
摘要：
The present invention provides a compound of formula I: wherein R1, R2, R2′ and X′ are as defined and described herein, methods of manufacture thereof and compositions thereof, useful for example as peripheral mu opioid receptor antagonists in treatment of side effects of opioid administration.
公开/授权文献
- US08546418B2 Peripheral opioid receptor antagonists and uses thereof 公开/授权日：2013-10-01
信息查询
IPC分类:
