发明申请
US20110190491A1 S-TRIAZOLE ALPHA- MERCAPTOACETANILIDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE
有权
作为艾滋病病毒逆转录酶的抑制剂的S-三唑阿美巴司他胺
- 专利标题: S-TRIAZOLE ALPHA- MERCAPTOACETANILIDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE
- 专利标题(中): 作为艾滋病病毒逆转录酶的抑制剂的S-三唑阿美巴司他胺
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申请号: US13081398申请日: 2011-04-06
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公开(公告)号: US20110190491A1公开(公告)日: 2011-08-04
- 发明人: Jean-Luc Girardet , Yung-Hyo Koh , Martha De La Rosa , Esmir Gunic , Zhi Hong , Stanley Lang , Woo-Hong Kim
- 申请人: Jean-Luc Girardet , Yung-Hyo Koh , Martha De La Rosa , Esmir Gunic , Zhi Hong , Stanley Lang , Woo-Hong Kim
- 申请人地址: US CA San Diego
- 专利权人: Ardea Biosciences, Inc.
- 当前专利权人: Ardea Biosciences, Inc.
- 当前专利权人地址: US CA San Diego
- 主分类号: C07D249/12
- IPC分类号: C07D249/12 ; C07D413/12 ; C07D401/12
摘要:
A series of S-triazolyl α-mercaptoacetanilides having general structure (1) are provided, where Q is CO2H, CONR2, SO3H, or SO2NR2. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.