发明申请
US20110195018A1 LOW MOLECULAR WEIGHT THYROID STIMULATING HORMONE RECEPTOR (TSHR) AGONISTS
有权
低分子量甲状腺刺激激素受体(TSHR)激素
- 专利标题: LOW MOLECULAR WEIGHT THYROID STIMULATING HORMONE RECEPTOR (TSHR) AGONISTS
- 专利标题(中): 低分子量甲状腺刺激激素受体(TSHR)激素
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申请号: US13125045申请日: 2008-10-20
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公开(公告)号: US20110195018A1公开(公告)日: 2011-08-11
- 发明人: Marvin C. Gershengorn , Susanne Neumann , Bruce M. Raaka , Craig J. Thomas , James Inglese , Noel T. Southall , Steven Titus , Wei Zheng , Wenwei Huang , Gerd Krause , Gunnar Kleinau
- 申请人: Marvin C. Gershengorn , Susanne Neumann , Bruce M. Raaka , Craig J. Thomas , James Inglese , Noel T. Southall , Steven Titus , Wei Zheng , Wenwei Huang , Gerd Krause , Gunnar Kleinau
- 国际申请: PCT/US2008/011958 WO 20081020
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; C07D239/88 ; C07D217/24 ; A61K31/47 ; A61P35/00 ; A61K31/167 ; A61K31/517 ; C07C233/01
摘要:
Disclosed are oxo-hydroquinazolines that are useful as selective TSHR agonists. The compounds may be used for detecting or treating thyroid cancer, or treating a bone degenerative disorder.
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