In a hard-disc drive read channel, frequency-based measures are generated at two different data frequencies (e.g., 2T and DC) by applying a transform, such as a discrete Fourier transform (DFT), to signal values, such as ADC or equalizer output values, corresponding to, e.g., a 2T data pattern stored on the hard disc. The frequency-based measures are used to detect defect regions on the hard disc and/or to classify defect regions as being due to either thermal asperity (TA) or drop-out media defect (MD).