发明申请
US20110207712A1 Phosphatidylinositol 3-Kinase Inhibitors And Methods Of Their Use
有权
磷脂酰肌醇3-激酶抑制剂及其使用方法
- 专利标题： Phosphatidylinositol 3-Kinase Inhibitors And Methods Of Their Use
- 专利标题（中）： 磷脂酰肌醇3-激酶抑制剂及其使用方法
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申请号： US13096942申请日： 2011-04-28
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公开(公告)号： US20110207712A1公开(公告)日： 2011-08-25
- 发明人: William Bajjalieh , Lynne Canne Bannen , S. David Brown , Patrick Kearney , Morrison Mac , Charles K. Marlowe , John M. Nuss , Zerom Tesfai , Yong Wang , Wei Xu
- 申请人： William Bajjalieh , Lynne Canne Bannen , S. David Brown , Patrick Kearney , Morrison Mac , Charles K. Marlowe , John M. Nuss , Zerom Tesfai , Yong Wang , Wei Xu
- 申请人地址： US CA So. San Francisco
- 专利权人： Exelixis, Inc.
- 当前专利权人： Exelixis, Inc.
- 当前专利权人地址： US CA So. San Francisco
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; A61K31/498 ; C07D487/04 ; C07D241/54 ; A61K31/4985 ; C07D413/12 ; C07D401/12 ; A61P35/00
摘要：
The present invention comprises small molecule inhibitors of phosphatidylinositol 3-kinase (PI3K), which is associated with a number of malignancies such as ovarian cancer, cervical cancer, breast cancer, colon cancer, rectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases.
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