发明申请
- 专利标题： Diversion- and/or abuse-resistant aompositions and methods for making the same
- 专利标题（中）： 转移和/或滥用抗性的组合物及其制备方法
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申请号： US12660268申请日： 2010-02-24
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公开(公告)号： US20110207761A1公开(公告)日： 2011-08-25
- 发明人: Mikhail Viktorovich Losev , Alexandr Vasilievich Troisky , Michael Libman , Vadim Zolotarsky
- 申请人： Mikhail Viktorovich Losev , Alexandr Vasilievich Troisky , Michael Libman , Vadim Zolotarsky
- 主分类号： A61K31/485
- IPC分类号： A61K31/485 ; A61K31/137
摘要：
A composition formulated for diversion- and/or abuse-resistance, includes at least one active pharmaceutical ingredient (API), each present in an acidic form, a first compound capable of coupling to the acidic form of the API to form a complex, where the resulting complex is resistant to separation by conventional separation methods, and a second compound capable of preferentially coupling to the first compound to thereby release the API from the complex.