发明申请
- 专利标题: PROCESS FOR THE PREPARATION OF BENZONORGORNENES
- 专利标题(中): 制备苯并呋喃的方法
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申请号: US13126380申请日: 2009-09-28
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公开(公告)号: US20110207958A1公开(公告)日: 2011-08-25
- 发明人: Denis Gribkov , Bjorn Antelmann , Fanny Giordano , Harald Walter , Alain De Mesmaeker
- 申请人: Denis Gribkov , Bjorn Antelmann , Fanny Giordano , Harald Walter , Alain De Mesmaeker
- 申请人地址: US NC Greensboro
- 专利权人: SYNGENTA CROP PROTECTION LLC
- 当前专利权人: SYNGENTA CROP PROTECTION LLC
- 当前专利权人地址: US NC Greensboro
- 优先权: EP08018721.4 20081027; EP09161388.5 20090528
- 国际申请: PCT/EP09/62525 WO 20090928
- 主分类号: C07C203/00
- IPC分类号: C07C203/00 ; C07C209/36 ; C07C17/32
摘要:
The present invention relates to a novel a process for the preparation of 9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-ylamine which process comprises a) reacting cyclopentadiene in the presence of a radical initiator and CXCI3, wherein X is chloro or bromo, to a compound of formula I1, or aa) reacting cyclopentadiene with CXCI3, wherein X is chloro, in the presence of a metal catalyst to a compound of formula I1, wherein X is chloro, b) reacting the compound of formula I1 with a base in the presence of an appropriate solvent to the compound of formula III, c) and converting the compound of formula III in the presence of 1,2-dehydro-6-nitrobenzene to the compound of formula IV, and d) hydrogenating the compound of formula IV in the presence of a metal catalyst.
公开/授权文献
- US09115043B2 Process for the preparation of benzonorbornenes 公开/授权日:2015-08-25
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