发明申请
- 专利标题： INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE
- 专利标题（中）： 二乙酰胆碱酯酶抑制剂
-
申请号： US13129821申请日： 2009-11-17
-
公开(公告)号： US20110224193A1公开(公告)日： 2011-09-15
- 发明人: Pauline C. Ting , Robert Aslanian , Jianhua Cao , Mary Ann Caplen , Tin-Yau Chan , Hyunjin Kim , Jae-Hun Kim , Rongze Kuang , Joe F. Lee , Heping Wu
- 申请人： Pauline C. Ting , Robert Aslanian , Jianhua Cao , Mary Ann Caplen , Tin-Yau Chan , Hyunjin Kim , Jae-Hun Kim , Rongze Kuang , Joe F. Lee , Heping Wu
- 专利权人： MERCK SHARP & DOHME CORP
- 当前专利权人： MERCK SHARP & DOHME CORP
- 国际申请： PCT/US09/64762 WO 20091117
- 主分类号： A61K31/5513
- IPC分类号： A61K31/5513 ; C07D413/14 ; A61K31/4545 ; A61K31/497 ; A61P3/00 ; A61P3/04 ; A61P3/10 ; A61P9/00 ; A61P3/08
摘要：
The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase (“DGAT”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown with this abstract.