发明申请
- 专利标题: Novel Lactams as Beta Secretase Inhibitors
- 专利标题(中): 新型乳酸内切酶作为分泌酶抑制剂
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申请号: US13130192申请日: 2009-11-12
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公开(公告)号: US20110224231A1公开(公告)日: 2011-09-15
- 发明人: Michael A. Brodney , Ivan V. Efremov , Christopher J. Helal , Brian T. O'Neill
- 申请人: Michael A. Brodney , Ivan V. Efremov , Christopher J. Helal , Brian T. O'Neill
- 申请人地址: US CT Groton
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 当前专利权人地址: US CT Groton
- 国际申请: PCT/IB2009/055043 WO 20091112
- 主分类号: A61K31/4965
- IPC分类号: A61K31/4965 ; C07D471/10 ; A61K31/438 ; A61P25/00 ; A61P25/18
摘要:
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment methods of synthesis, and intermediates are also disclosed.