- 专利标题: CATHEPSIN CYSTEINE PROTEASE INHIBITORS
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申请号: US13115462申请日: 2011-05-25
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公开(公告)号: US20110230446A1公开(公告)日: 2011-09-22
- 发明人: Christopher I. Bayly , Cameron Black , Serge Leger , Chun Sing Li , Dan McKay , Chirstophe Mellon , Jacques Yves Gauthier , Vouy-Linh Truong , Cheuk Lau , Michel Therien , Michael J. Green , Bernard L. Hirschbein , James William Janc , James T. Palmer , Chitra Baskaran
- 申请人: Christopher I. Bayly , Cameron Black , Serge Leger , Chun Sing Li , Dan McKay , Chirstophe Mellon , Jacques Yves Gauthier , Vouy-Linh Truong , Cheuk Lau , Michel Therien , Michael J. Green , Bernard L. Hirschbein , James William Janc , James T. Palmer , Chitra Baskaran
- 申请人地址: US CA South San Francisco CA Kirkland
- 专利权人: Axys Pharmaceuticals, Inc.,Merck Canada Inc.
- 当前专利权人: Axys Pharmaceuticals, Inc.,Merck Canada Inc.
- 当前专利权人地址: US CA South San Francisco CA Kirkland
- 主分类号: A61K31/277
- IPC分类号: A61K31/277 ; A61K31/495 ; A61K31/4418 ; A61K31/426 ; A61K31/4174 ; A61K31/663 ; A61P19/08 ; A61P19/10 ; A61P1/02 ; A61P19/02 ; A61P35/00 ; A61P19/00
摘要:
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
公开/授权文献
- US08318748B2 Cathepsin cysteine protease inhibitors 公开/授权日:2012-11-27