An E-paper display device with touch sensing function includes a composite transparent electrodes layer including at least one layer of touch electrodes responding to a touch, a pixel electrode, and an electrophoretic medium contacting the composite transparent electrodes layer and arranged between the composite transparent electrodes layer and the pixel electrode. One of the at least one layer of touch electrodes forms a display layer with the pixel electrode and the electrophoretic medium. A driving circuit configured to detect the location of a user touch on the composite transparent electrodes layer and drive the electrophoretic medium layer for displaying content. With the use of the composite transparent electrodes layer, the light propagation efficiency can be effectively improved, and the manufacturing technology is simplified.