发明申请
- 专利标题： NOVEL PEPTIDES AND METHODS FOR THEIR PREPARATION AND USE
- 专利标题（中）： 新型肽及其制备和使用方法
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申请号： US13069425申请日： 2011-03-23
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公开(公告)号： US20110237503A1公开(公告)日： 2011-09-29
- 发明人: Jorge ALSINA-FERNANDEZ , Krister Bengt BOKVIST , Lili GUO , John Philip MAYER
- 申请人： Jorge ALSINA-FERNANDEZ , Krister Bengt BOKVIST , Lili GUO , John Philip MAYER
- 申请人地址： US IN Indianapolis
- 专利权人： ELI LILLY AND COMPANY
- 当前专利权人： ELI LILLY AND COMPANY
- 当前专利权人地址： US IN Indianapolis
- 主分类号： A61K38/22
- IPC分类号： A61K38/22 ; C07K14/575 ; A61P3/04 ; A61P3/10
摘要：
The present invention is in the field of treatment of diabetes and relates to peptides that exhibit activity for both glucose-dependent insulinotropic peptide receptor (GIP-R) and glucagon-like peptide-1 receptor (GLP-1-R) and are selective over glucagon receptor (Gluc-R). Specifically provided are GIP analogs with amino acid substitutions introduced to modulate activity for both GIP-R and GLP-1-R and maintain selectivity over Gluc-R.
公开/授权文献
- US08815811B2 Peptides and methods for their preparation and use 公开/授权日：2014-08-26
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