Techniques for performing interference management to support peer-to-peer (P2P) communication in a wide area network (WAN) are described. In an aspect, interference management may be performed in a coordinated manner for/by a set of server nodes, which may include a P2P server and at least one neighbor server node of the P2P server. The P2P server may be a UE communicating peer-to-peer with at least one other UE or P2P client. Interference management may be performed for the set of server nodes to reduce interference to the P2P server and/or the at least one P2P client. In one design, active sets may be determined for UEs. The active set of each UE may include nodes received with sufficient strength by that UE. The set of server nodes may be determined based on the active sets of the P2P server, the at least one P2P client, and possibly other UEs.