发明申请
- 专利标题: Modified Pyrazine Derivatives and Uses Thereof
- 专利标题(中): 改性吡嗪衍生物及其用途
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申请号: US13140082申请日: 2009-12-17
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公开(公告)号: US20110250139A1公开(公告)日: 2011-10-13
- 发明人: Amruta Poreddy , William L. Neumann
- 申请人: Amruta Poreddy , William L. Neumann
- 国际申请: PCT/US09/68453 WO 20091217
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; A61P13/12 ; A61P13/10 ; C07D241/20 ; A61K31/4965
摘要:
Provided herein are compounds, preparations and formulations comprising pyrazine derivatives having multiple poly(ethylene glycol) containing substituents. Many of the compounds disclosed herein are excretable by the renal system of a subject or patient and are useful for visualizing the renal system of a subject or patient. Upon excitation by electromagnetic radiation, a number of the compounds disclosed herein exhibit luminescence and are externally detectable when present in the body fluid of a patient or subject. Also provided herein are methods for visualizing the renal system of a subject or patient.
公开/授权文献
- US08703100B2 Modified pyrazine derivatives and uses thereof 公开/授权日:2014-04-22