发明申请
- 专利标题: GAMMA SECRETASE MODULATORS
- 专利标题(中): GAMMA秘密调节器
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申请号: US12671782申请日: 2008-08-04
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公开(公告)号: US20110257163A1公开(公告)日: 2011-10-20
- 发明人: Anandan Palani , Jun Qin , Xiaohong Zhu , Robert G. Aslanian , Mark D. McBriar
- 申请人: Anandan Palani , Jun Qin , Xiaohong Zhu , Robert G. Aslanian , Mark D. McBriar
- 专利权人: Schering Corporation
- 当前专利权人: Schering Corporation
- 国际申请: PCT/US08/09368 WO 20080804
- 主分类号: A61K31/541
- IPC分类号: A61K31/541 ; A61K31/4164 ; C07D417/10 ; A61P27/06 ; A61P25/00 ; A61P25/28 ; A61P3/06 ; C07D233/61 ; A61K31/427
摘要:
This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula Compounds of formula (I) include compounds of formulas (IA) and (IB). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).
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