发明申请
US20110262567A1 COMPOSITION FOR TREATING GOUT, CONTAINING ANGELICA GIGAS EXTRACT HAVING A XANTHINE OXIDASE-INHIBITING EFFECT AND AN INFLAMMATION-INDUCING ENZYME-INHIBITING EFFECT
审中-公开
用于治疗GOUT的组合物，包含具有XANTHINE氧化酶抑制作用的ANGELICA GIGAS提取物和炎症诱导的酶抑制效应
- 专利标题： COMPOSITION FOR TREATING GOUT, CONTAINING ANGELICA GIGAS EXTRACT HAVING A XANTHINE OXIDASE-INHIBITING EFFECT AND AN INFLAMMATION-INDUCING ENZYME-INHIBITING EFFECT
- 专利标题（中）： 用于治疗GOUT的组合物，包含具有XANTHINE氧化酶抑制作用的ANGELICA GIGAS提取物和炎症诱导的酶抑制效应
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申请号： US13141631申请日： 2009-12-16
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公开(公告)号： US20110262567A1公开(公告)日： 2011-10-27
- 发明人: Jae Seon Kang , Jin Young Lee , Yun Jung Park , Jae Yeon Park , Kang Min Kim , Min Hui Park , Ik Hwan Kim , Yong Geun Hong , Min Su Jeong , Woo Sik Jeong , Seon Ok
- 申请人： Jae Seon Kang , Jin Young Lee , Yun Jung Park , Jae Yeon Park , Kang Min Kim , Min Hui Park , Ik Hwan Kim , Yong Geun Hong , Min Su Jeong , Woo Sik Jeong , Seon Ok
- 申请人地址： KR GYEONGSANGNAM
- 专利权人： KOREA BIO HEALTH CO., LTD.
- 当前专利权人： KOREA BIO HEALTH CO., LTD.
- 当前专利权人地址： KR GYEONGSANGNAM
- 优先权： KR10-2008-0132592 20081223
- 国际申请： PCT/KR09/07549 WO 20091216
- 主分类号： A61K36/232
- IPC分类号： A61K36/232 ; A61P19/06
摘要：
The present invention relates to a composition for the treatment of gout, comprising an Angelica gigas Nakai extract which inhibits xanthine oxidase to reduce uric acid in the blood or urine, thereby being effective in the treatment of gout.Further, the present invention relates to a composition for the prevention of inflammation in gout, comprising an Angelica gigas Nakai extract which has an inhibitory effect on the inflammation-inducing enzyme Cox-2.The Angelica gigas Nakai extract of the present invention is a liquid concentrate consisting of 98% by weight or more of decursin and decursinol angelate as main ingredients, and for administration to human, it is extracted with water and ethanol only as an extraction solvent. In addition, a purification method using a difference in temperature and solubility is used, in order to increase its purity.
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