Invention Application
US20110263558A1 Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases
有权
Azetidines作为MEK抑制剂治疗增殖性疾病
- Patent Title: Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases
- Patent Title (中): Azetidines作为MEK抑制剂治疗增殖性疾病
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Application No.: US13048832Application Date: 2011-03-15
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Publication No.: US20110263558A1Publication Date: 2011-10-27
- Inventor: Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R. Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
- Applicant: Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R. Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
- Applicant Address: US CA South San Francisco
- Assignee: EXELIXIS, INC.
- Current Assignee: EXELIXIS, INC.
- Current Assignee Address: US CA South San Francisco
- Main IPC: A61K31/397
- IPC: A61K31/397 ; C07D413/06 ; C07D401/04 ; A61P35/00 ; C07D471/04 ; C07D403/04 ; C07D401/06 ; A61K31/5377 ; C07D205/04 ; C07D403/06
Abstract:
Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
Public/Granted literature
- US08362002B2 Azetidines as MEK inhibitors for the treatment of proliferative diseases Public/Granted day:2013-01-29
Information query
