发明申请
US20110263581A1 FUSED TRICYCLIC COMPOUNDS AS SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS
有权
作为丝氨酸蛋白激酶激酶和PARP调节剂的融合三聚体化合物
- 专利标题： FUSED TRICYCLIC COMPOUNDS AS SERINE-THREONINE PROTEIN KINASE AND PARP MODULATORS
- 专利标题（中）： 作为丝氨酸蛋白激酶激酶和PARP调节剂的融合三聚体化合物
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申请号： US13035640申请日： 2011-02-25
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公开(公告)号： US20110263581A1公开(公告)日： 2011-10-27
- 发明人: Peter C. CHUA , Fabrice Pierre , Jeffrey P. Whitten
- 申请人： Peter C. CHUA , Fabrice Pierre , Jeffrey P. Whitten
- 申请人地址： US CA San Diego
- 专利权人： CYLENE PHARMACEUTICALS, INC.
- 当前专利权人： CYLENE PHARMACEUTICALS, INC.
- 当前专利权人地址： US CA San Diego
- 主分类号： A61K31/54
- IPC分类号： A61K31/54 ; A61K31/519 ; A61K31/4745 ; C07D495/04 ; A61K31/4743 ; C12N9/99 ; A61K31/5377 ; A61K31/496 ; C07D417/14 ; A61P35/00 ; C12N5/09 ; C07D471/04 ; C07D413/14
摘要：
The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate casein kinase (CK) activity and/or poly(ADP-ribose)polymerase (PARP) activity. The invention also relates in part to methods for using such molecules.
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