Invention Application
US20110263670A1 NOVEL POLYMORPHS OF SUNITINIB AND PROCESSES FOR THEIR PREPARATION
审中-公开
SUNITINIB的新型聚合物及其制备方法
- Patent Title: NOVEL POLYMORPHS OF SUNITINIB AND PROCESSES FOR THEIR PREPARATION
- Patent Title (中): SUNITINIB的新型聚合物及其制备方法
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Application No.: US13060322Application Date: 2009-08-24
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Publication No.: US20110263670A1Publication Date: 2011-10-27
- Inventor: Vinayak Gore , Bharati Choudhari , Mahesh Hublikar , Prakash Bansode
- Applicant: Vinayak Gore , Bharati Choudhari , Mahesh Hublikar , Prakash Bansode
- Priority: IN1435/KOL/2008 20080825
- International Application: PCT/GB2009/051055 WO 20090824
- Main IPC: A61K31/404
- IPC: A61K31/404 ; A61P35/00 ; C07D403/06
Abstract:
The present invention relates to novel polymorphs of sunitinib free base designated form II and form III and to processes for their preparation. The invention also relates to their use as APIs and in the preparation of various forms of sunitinib. Further, the invention relates to pharmaceutical compositions comprising said novel polymorphs and salts, solvates and hydrates prepared according to the invention, and to the uses of said pharmaceutical compositions in the treatment and/or prevention of cancer.
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