- 专利标题: Compound with antimalarial activity and antimalarial drug containing the same as active ingredient
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申请号: US13067191申请日: 2011-05-16
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公开(公告)号: US20110275668A1公开(公告)日: 2011-11-10
- 发明人: Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- 申请人: Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- 申请人地址: JP Nagoya-shi
- 专利权人: Nagoya City University
- 当前专利权人: Nagoya City University
- 当前专利权人地址: JP Nagoya-shi
- 优先权: JP2006-049678 20060227
- 主分类号: A61K31/4709
- IPC分类号: A61K31/4709 ; A61P33/06 ; C07D215/46
摘要:
Compounds with high antimalarial activity; and antimalarial drugs containing the same as an active ingredient. There are provided compounds with antimalarial activity represented by the chemical formula: (wherein R1 is H, Cl or OCH3; R2 is H or CH3; R3 is CH, CH2, C(CH3), CH(CH3) or C(CH3)2; Ar is imidazole, triazole, pyridine, benzene, pyrrole, furan, thiophene or derivatives thereof; n is 1 to 5; and m is 1 to 5). Further, there are provided antimalarial drugs containing these compounds with antimalarial activity or pharmacologically acceptable salts thereof as active ingredients.