发明申请
US20110287016A1 NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P2F10B USEFUL IN TREATMENT AND DETECTION OF CANCER
有权
核酸和相关蛋白161P2F10B可用于治疗和检测癌症
- 专利标题： NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P2F10B USEFUL IN TREATMENT AND DETECTION OF CANCER
- 专利标题（中）： 核酸和相关蛋白161P2F10B可用于治疗和检测癌症
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申请号： US13153336申请日： 2011-06-03
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公开(公告)号： US20110287016A1公开(公告)日： 2011-11-24
- 发明人: Aya JAKOBOVITS , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jene Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
- 申请人： Aya JAKOBOVITS , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Wangmao Ge , Karen Jene Meyrick Morrison , Robert Kendall Morrison , Pia M. Challita-Eid
- 申请人地址： US CA Santa Monica
- 专利权人： AGENSYS, INC.
- 当前专利权人： AGENSYS, INC.
- 当前专利权人地址： US CA Santa Monica
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P35/00 ; C07K16/18 ; C07K16/46 ; C12N5/16 ; C12N15/63
摘要：
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization.