发明申请
- 专利标题: INHIBITION OF INFLUENZA M2 PROTON CHANNEL
- 专利标题(中): 抑制流感M2原子通道
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申请号: US13119052申请日: 2009-08-21
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公开(公告)号: US20110288111A1公开(公告)日: 2011-11-24
- 发明人: William F. DeGrado , Jun Wang
- 申请人: William F. DeGrado , Jun Wang
- 申请人地址: US PA Philadelphia
- 专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人地址: US PA Philadelphia
- 国际申请: PCT/US09/54603 WO 20090821
- 主分类号: A61K31/438
- IPC分类号: A61K31/438 ; C07D401/04 ; C07C211/38 ; A61K31/13 ; C07D491/113 ; A61P31/16 ; C07D215/06 ; A61K31/47 ; A61K31/4709 ; C07D233/64 ; A61K31/4164 ; C07D221/20 ; C07D495/10
摘要:
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 protein.
公开/授权文献
- US09453005B2 Inhibition of influenza M2 proton channel 公开/授权日:2016-09-27
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