发明申请
US20110293665A1 Recombinant Der P 2 Expressed in Pichia Pastoris as a "Natural-Like" Allergen for Immunotherapy and Diagnostic Purposes
有权
在巴斯德毕赤酵母中表达的重组Der P 2作为免疫治疗和诊断用途的“天然样”过敏原
- 专利标题： Recombinant Der P 2 Expressed in Pichia Pastoris as a "Natural-Like" Allergen for Immunotherapy and Diagnostic Purposes
- 专利标题（中）： 在巴斯德毕赤酵母中表达的重组Der P 2作为免疫治疗和诊断用途的“天然样”过敏原
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申请号： US13109491申请日： 2011-05-17
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公开(公告)号： US20110293665A1公开(公告)日： 2011-12-01
- 发明人: Véronique BORDAS , Laetitia Bussieres , Sabi Airouche , Sophie Tourdot , Emmanuel Nony , Philippe Moingeon , Julien Bouley
- 申请人： Véronique BORDAS , Laetitia Bussieres , Sabi Airouche , Sophie Tourdot , Emmanuel Nony , Philippe Moingeon , Julien Bouley
- 优先权： EP10305529.9 20100518
- 主分类号： A61K39/35
- IPC分类号： A61K39/35 ; C12P21/00 ; C07K14/435
摘要：
The present invention concerns a method for producing a recombinant Dermatophagoides pteronyssinus 2 protein (rDer p 2), comprising the steps of cultivating a Pichia pastoris yeast strain previously transformed with a rDer p 2 coding sequence, and isolating the rDer p 2 protein from said Pichia pastoris yeast strain. The invention also relates to compositions and kits comprising the rDer p 2 protein for therapeutic or diagnostic use.
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