发明申请
US20110294849A1 AMINOPYRAZOLE TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE
失效
C-MET蛋白激酶的氨基吡唑三唑并噻唑类抑制剂
- 专利标题: AMINOPYRAZOLE TRIAZOLOTHIADIAZOLE INHIBITOR OF C-MET PROTEIN KINASE
- 专利标题(中): C-MET蛋白激酶的氨基吡唑三唑并噻唑类抑制剂
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申请号: US13114215申请日: 2011-05-24
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公开(公告)号: US20110294849A1公开(公告)日: 2011-12-01
- 发明人: David J. Lauffer , Pan Li , Stefanie Roeper , Shereen Ibrahim , Anuj K. Kuldipkumar , Yi Shi , David B. Miller, JR.
- 申请人: David J. Lauffer , Pan Li , Stefanie Roeper , Shereen Ibrahim , Anuj K. Kuldipkumar , Yi Shi , David B. Miller, JR.
- 申请人地址: US MA Cambridge
- 专利权人: VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人: VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址: US MA Cambridge
- 主分类号: A61K31/4709
- IPC分类号: A61K31/4709 ; A61P35/00 ; A61P35/04 ; A61P9/10 ; A61P11/00 ; C07D513/04 ; A61P29/00
摘要:
The present invention relates to anhydrous and hydrated forms of Compound 1, which qre useful in the inhibition of c-Met protein kinase. The invention also provides pharmaceutically acceptable compositions comprising compounds of formula I and methods of using the compositions in the treatment of proliferative disorders.
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