发明申请
- 专利标题： CHEMICAL SYNTHESIS OF A HIGHLY POTENT EPOTHILONE
- 专利标题（中）： 高效液相色谱的化学合成
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申请号： US13213894申请日： 2011-08-19
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公开(公告)号： US20110301183A1公开(公告)日： 2011-12-08
- 发明人: Kyriacos C. Nicolaou , Benjamin Pratt , Stellios Arseniyadis
- 申请人： Kyriacos C. Nicolaou , Benjamin Pratt , Stellios Arseniyadis
- 优先权： USPCT/US2006/060710 20061109
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; C07D473/40 ; C07D417/06 ; C07D473/38 ; A61K31/428 ; A61P35/00 ; C07D493/04 ; C07D473/30
摘要：
A highly active synthetic epothilone compound whose activity exceeds that of either epothilone EpoA or EpoB when assayed as a cytotoxic agent against a cancer cell line is disclosed as is a pharmaceutical composition containing the synthetic epothilone.
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