发明申请
- 专利标题： THERAPEUTIC COMBINATION COMPRISING A CDKS INHIBITOR AND AN ANTINEOPLASTIC AGENT
- 专利标题（中）： 包含CDKS抑制剂和抗原药物的治疗组合
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申请号： US13055541申请日： 2009-07-29
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公开(公告)号： US20110312909A1公开(公告)日： 2011-12-22
- 发明人: Marina Ciomei , Aurelio Marsiglio , Valter Domenico Croci , Enrico Pesenti
- 申请人： Marina Ciomei , Aurelio Marsiglio , Valter Domenico Croci , Enrico Pesenti
- 申请人地址： IT Nerviano (MI)
- 专利权人： Nerviano Medical Sciences S.r.l.
- 当前专利权人： Nerviano Medical Sciences S.r.l.
- 当前专利权人地址： IT Nerviano (MI)
- 优先权： EP08161320.0 20080729
- 国际申请： PCT/EP2009/059815 WO 20090729
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K31/7068 ; A61B19/02 ; A61P35/00
摘要：
The present invention provides a therapeutic combination comprising (a) a compound of formula (I) as set forth in the specification and (b) one or more antineoplastic agents selected from the group consisting of alkylating or alkylating-like agents, antimetabolite agents and topoisomerase I inhibitors, wherein the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate thereof.
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