发明申请
US20110319401A1 FIVE CRYSTAL FORMS, METHODS OF PREPARATION, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS OF XLF-III-43
有权
五水晶形态，制备方法，药物组合物和XLF-III-43的应用
- 专利标题： FIVE CRYSTAL FORMS, METHODS OF PREPARATION, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS OF XLF-III-43
- 专利标题（中）： 五水晶形态，制备方法，药物组合物和XLF-III-43的应用
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申请号： US13131492申请日： 2009-11-28
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公开(公告)号： US20110319401A1公开(公告)日： 2011-12-29
- 发明人: Yang Lv , Xiaoguang Chen , Ping Xie , Li Zhang , Cheng Wang
- 申请人： Yang Lv , Xiaoguang Chen , Ping Xie , Li Zhang , Cheng Wang
- 申请人地址： CN Beijing
- 专利权人： INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
- 当前专利权人： INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES
- 当前专利权人地址： CN Beijing
- 优先权： CN200810227626.0 20081128
- 国际申请： PCT/CN2009/075196 WO 20091128
- 主分类号： A61K31/539
- IPC分类号： A61K31/539 ; A61P13/12 ; A61P35/00 ; A61P9/12 ; A61P3/10 ; C07D498/14 ; A61P9/00
摘要：
This invention discloses that the five crystal forms of XLF-III-43 can be used as crude drugs. The invention also relates to the preparation methods of the five crystal forms of XLF-III-43 as crude drugs, to the applications of the sterling of the five crystal forms of XLF-III-43 and mixed crystals in different proportions as medicinally active components to develop various kinds of medicines and compound medicines. In addition, this invention also relates to applying the crystal samples of XLF-III-43 as crude drugs to treat kidney dysfunction, cardiocerebral vessel diseases, hypertension, type II diabetic mellitus, complications of hypertension and diabetic mellitus, tumor, precancerosis, edema, and achieves therapeutic effects by enhancing blood drug levels resulted from effects of crystal forms in the processes of treating all kinds of diseases.
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