发明申请
- 专利标题: Tumour Cell Lines and Uses Thereof
- 专利标题(中): 肿瘤细胞系及其用途
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申请号: US13208253申请日: 2011-08-11
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公开(公告)号: US20110319590A1公开(公告)日: 2011-12-29
- 发明人: Steffen Goletz , Hans Baumeister , Marion Schlangstedt , Ute SCHÖBER
- 申请人: Steffen Goletz , Hans Baumeister , Marion Schlangstedt , Ute SCHÖBER
- 申请人地址: DE Berlin
- 专利权人: GLYCOTOPE GmbH
- 当前专利权人: GLYCOTOPE GmbH
- 当前专利权人地址: DE Berlin
- 优先权: EP03018576.3 20030818
- 主分类号: C07K14/62
- IPC分类号: C07K14/62 ; C07K14/435 ; C07K14/575 ; C07K14/52 ; C07K14/54 ; C07K14/59 ; C07K14/53 ; C07K14/55 ; C12P21/02 ; C07K16/18
摘要:
The present invention relates to a cell line selected from the group consisting of (a) a cell line denominated NM-F9 having the DSMZ accession number DSM ACC2606; (b) a cell line denominated NM-D4 having the DSMZ accession number DSM ACC2605; and subclones of (a) or (b). Additionally, the present invention provides a lysate of the cell lines or a molecule or mixture of molecules obtained from these cell lines as well as dendritic cells loaded with said lysate, co-cultivated or fused with cells from the cell lines, or a molecule or mixture of molecules obtained from these cell lines of the present invention. Moreover compositions, preferably pharmaceutical or vaccine compositions are provided which comprise the cell lines, lysate, molecules, mixture of molecules or dendritic cells of the present invention. In another aspect the present invention relates to methods for producing the aforementioned compositions. Furthermore, methods and uses for vaccination against or treatment or prevention of cancers and/or tumourous diseases are provided.
公开/授权文献
- US08283161B2 Tumour cell lines and uses thereof 公开/授权日:2012-10-09
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