发明申请
US20120003327A1 METHOD OF REDUCING MULTI-DRUG RESISTANCE USING INOSITOL TRIPYROPHOSPHATE
审中-公开
使用磷酸二氢铁磷酸盐降低多药耐药性的方法
- 专利标题: METHOD OF REDUCING MULTI-DRUG RESISTANCE USING INOSITOL TRIPYROPHOSPHATE
- 专利标题(中): 使用磷酸二氢铁磷酸盐降低多药耐药性的方法
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申请号: US13033363申请日: 2011-02-23
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公开(公告)号: US20120003327A1公开(公告)日: 2012-01-05
- 发明人: Yves Claude NICOLAU , Jean-Marie LEHN , Claudine KIEDA
- 申请人: Yves Claude NICOLAU , Jean-Marie LEHN , Claudine KIEDA
- 主分类号: A61K31/6615
- IPC分类号: A61K31/6615 ; A61P35/00 ; A61K33/24
摘要:
Inositol trisphosphate (ITPP) causes normalization of tumor vasculature and is a particularly effective cancer therapy when a second chemotherapeutic agent is administered following partial vascularization. ITPP also treats, alone or in combination, multi-drug resistant cancers. ITPP can also be used to reduce the amount of a second chemotherapeutic drug required for anticancer activity. In addition, ITPP enhances immune response and treats hyperproliferative disorders.
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