发明申请
- 专利标题： Novel single nucleotide polymorphisms and community-associated methicillin-resistant staphylococcus aureus
- 专利标题（中）： 新型单核苷酸多态性和社区相关耐甲氧西林金黄色葡萄球菌
-
申请号： US13068331申请日： 2011-05-09
-
公开(公告)号： US20120009572A1公开(公告)日： 2012-01-12
- 发明人: Scott E. Gygax , Sean Chadwick , Aditya Prasad , Martin E. Adelson , Eli Mordechai
- 申请人： Scott E. Gygax , Sean Chadwick , Aditya Prasad , Martin E. Adelson , Eli Mordechai
- 申请人地址： US NJ Hamilton
- 专利权人： Medical Diagnostic Laboratories, LLC
- 当前专利权人： Medical Diagnostic Laboratories, LLC
- 当前专利权人地址： US NJ Hamilton
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention is based on the discovery of novel polymorphisms (SNPs) in the penicillin binding protein (pbp3) gene in Staphylococcus aureus. The presence of G88A and/or G2047A SNPs provides an accurate, reliable biomarker for the presence of Methicillin Resistant Staphylococcus aureus (MRSA), specifically the community-associated MRSA (CA-MRSA). The present invention provides reagents used for detecting the SNPs as well as methods of identifying and using these variants to screen subjects for presence of CA-MRSA. The methods involve isolating a biological sample from a mammal (preferably a human) and testing for the presence of a SNP in the pbp3 gene which is associated with CA-MRSA.
公开/授权文献
信息查询
