A method and apparatus to manage a database in which a data file and an index file are efficiently disposed include generating a table space in such a way that a region of a database in which data in a table form is stored is allocated to a first storage device, and a region of the database in which index information used to search for the data is stored is allocated to a second storage device, storing the data in table form in the first storage device and the index information in the second storage device according to the table space, and storing the data in the database or searching the database according to an input query.