One aspect of the present invention includes a light-emitting diode (LED) power supply system. The system includes an LED regulator configured to monitor at least one LED voltage associated with a respective at least one activated LED string and to generate an LED regulation voltage based on the at least one LED voltage relative to an LED power voltage that provides power to the at least one activated LED string. The system also includes a power converter configured to generate the LED power voltage and to regulate the LED power voltage based on the LED regulation voltage.