发明申请
- 专利标题： POLYMER-BASED, SUSTAINED RELEASE DRUG DELIVERY SYSTEM
- 专利标题（中）： 基于聚合物，持续释放药物递送系统
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申请号： US13185664申请日： 2011-07-19
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公开(公告)号： US20120016467A1公开(公告)日： 2012-01-19
- 发明人: Jianbing Chen , Paul Ashton , Thomas J. Smith
- 申请人： Jianbing Chen , Paul Ashton , Thomas J. Smith
- 申请人地址： US MA Watertown
- 专利权人： pSivida Inc.
- 当前专利权人： pSivida Inc.
- 当前专利权人地址： US MA Watertown
- 主分类号： A61F2/82
- IPC分类号： A61F2/82 ; A61K31/58 ; A61K31/7064 ; A61K31/7068 ; A61K31/706 ; A61K31/7076 ; A61K31/52 ; A61K9/00 ; A61P29/00 ; A61P35/00 ; A61P37/00 ; A61P33/00 ; A61P27/06 ; A61P31/00 ; A61P31/12 ; A61K31/513
摘要：
Disclosed is a sustained release system that includes a polymer and a prodrug having a solubility less than about 1 mg/ml dispersed in the polymer. Advantageously, the polymer is permeable to the prodrug and may be non-release rate limiting with respect to the rate of release of the prodrug from the polymer. This permits improved drug delivery within a body in the vicinity of a surgery via sustained release rate kinetics over a prolonged period of time, while not requiring complicated manufacturing processes.
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