发明申请
- 专利标题: NOVEL INHIBITOR OF ANGIOGENESIS
- 专利标题(中): 新生血管生成抑制剂
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申请号: US13142541申请日: 2008-07-04
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公开(公告)号: US20120021974A1公开(公告)日: 2012-01-26
- 发明人: Taavi Pall , Wally Anderson , Lagle Kasak , Anne Pink , Priit Kogerman , Aire Allikas , Andres Valkna
- 申请人: Taavi Pall , Wally Anderson , Lagle Kasak , Anne Pink , Priit Kogerman , Aire Allikas , Andres Valkna
- 申请人地址: EE Tallinn
- 专利权人: IBCC HOLDING AS
- 当前专利权人: IBCC HOLDING AS
- 当前专利权人地址: EE Tallinn
- 优先权: US60949518 20070713
- 国际申请: PCT/EP2008/058697 WO 20080704
- 主分类号: A61K38/17
- IPC分类号: A61K38/17 ; A61P35/00 ; A61P9/10 ; A61P29/00 ; A61P17/06 ; A61P27/02 ; C07K14/47 ; A61P35/04
摘要:
The invention relates to a method of treatment for states related to inhibition of angiogenesis and endothelial cell proliferation comprising administering an effective amount of vimentin or its derivatives or its fragments, to a subject in need thereof. Further, the invention relates to a pharmaceutical composition and a medicament comprising vimentin, as well as the use of vimentin in the manufacture of a medicament. Hereby, angiogenesis and endothelial cell proliferation can be controlled, and therapeutic treatment for related states is provided.
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