Invention Application
US20120022028A1 SGC STIMULATORS OR SGC ACTIVATORS IN COMBINATION WITH PDE5 INHIBITORS FOR THE TREATMENT OF ERECTILE DYSFUNCTION
审中-公开
SGC刺激剂或SGC激活剂与PDE5抑制剂联合治疗溃疡性功能障碍
- Patent Title: SGC STIMULATORS OR SGC ACTIVATORS IN COMBINATION WITH PDE5 INHIBITORS FOR THE TREATMENT OF ERECTILE DYSFUNCTION
- Patent Title (中): SGC刺激剂或SGC激活剂与PDE5抑制剂联合治疗溃疡性功能障碍
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Application No.: US13144929Application Date: 2010-01-07
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Publication No.: US20120022028A1Publication Date: 2012-01-26
- Inventor: Peter Sandner , Johannes-Peter Stasch , Michael-Friedrich Böttcher
- Applicant: Peter Sandner , Johannes-Peter Stasch , Michael-Friedrich Böttcher
- Applicant Address: DE Berlin
- Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
- Current Assignee Address: DE Berlin
- Priority: EP09000619.8 20090117; EP09002177.5 20090217
- International Application: PCT/EP2010/000029 WO 20100107
- Main IPC: A61K31/635
- IPC: A61K31/635 ; A61K31/53 ; A61P15/10 ; A61K31/519 ; A61K31/4985 ; A61K31/5377 ; A61K31/506
Abstract:
The present invention relates to soluble guanylate cyclase (sGC) and to phosphodiesterases (PDEs) and the pharmacology of sGC stimulators, sGC activators and PDE inhibitors. More particularly, the invention relates to the use of sGC stimulators and sGC activators in combination with PDE5 inhibitors for preparation of medicaments for the treatment of male erectile dysfunction (MED) in particular for the MED treatment of difficult to treat patients and patients not or not fully responding to PDE5 inhibitors.
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