发明申请
US20120022057A1 BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE
审中-公开
双酚化合物作为抑制剂的双环化合物
- 专利标题： BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE
- 专利标题（中）： 双酚化合物作为抑制剂的双环化合物
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申请号： US13256468申请日： 2010-03-16
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公开(公告)号： US20120022057A1公开(公告)日： 2012-01-26
- 发明人: Gang Zhou , Grant Wishart , Pauline C. Ting , Robert G. Aslanian , Nicolas Zorn , Jianhua Cao
- 申请人： Gang Zhou , Grant Wishart , Pauline C. Ting , Robert G. Aslanian , Nicolas Zorn , Jianhua Cao
- 申请人地址： US NJ Kenilworth
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： US NJ Kenilworth
- 国际申请： PCT/US2010/027446 WO 20100316
- 主分类号： A61K31/538
- IPC分类号： A61K31/538 ; C07D403/06 ; C07D265/36 ; C07D241/38 ; C07D215/50 ; C07D209/42 ; C07D401/06 ; C07D413/06 ; C07D405/12 ; C07D401/12 ; C07D417/12 ; C07D215/233 ; A61K31/404 ; A61K31/498 ; A61K31/47 ; A61K31/4439 ; A61K31/454 ; A61K31/5377 ; A61K31/4178 ; A61K31/4709 ; A61P3/04 ; A61P3/00 ; A61P3/10 ; C07D209/08
摘要：
The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase (“DGAT”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown below (I).
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