发明申请
- 专利标题： Plasminogen Activator Inhibitor-1 Inhibitor
- 专利标题（中）： 纤溶酶原激活物抑制剂-1抑制剂
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申请号： US13262259申请日： 2010-03-31
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公开(公告)号： US20120022080A1公开(公告)日： 2012-01-26
- 发明人: Toshio Miyata , Kenji Murano , Nagahisa Yamaoka , Akihisa Maeda
- 申请人： Toshio Miyata , Kenji Murano , Nagahisa Yamaoka , Akihisa Maeda
- 申请人地址： JP Tokyo
- 专利权人： RENASCIENCE CO., LTD.
- 当前专利权人： RENASCIENCE CO., LTD.
- 当前专利权人地址： JP Tokyo
- 优先权： JP2009-088400 20090331
- 国际申请： PCT/IB10/00731 WO 20100331
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; C07C233/88 ; C07D409/12 ; C07D333/24 ; C07D213/56 ; C07D405/10 ; C07D215/14 ; C07D217/16 ; C07D295/16 ; A61K31/341 ; A61K31/196 ; A61K31/381 ; A61K31/4418 ; A61K31/4025 ; A61K31/4525 ; A61K31/47 ; A61K31/472 ; A61P7/02 ; A61P9/10 ; A61P35/00 ; A61P27/06 ; A61P3/10 ; A61P25/28 ; A61P3/04 ; C07D307/54
摘要：
The present invention provides a novel compound having plasminogen activator inhibitor-1 inhibitory activity, and an inhibitor of PAI-1 comprising the compound as an active ingredient. The present invention also provides a pharmaceutical composition having an inhibitory action on PAI-1 activity and being efficacious in the prevention and treatment of various diseases whose onset is associated with PAI-1 activity.
公开/授权文献
- US08785473B2 Plasminogen activator inhibitor-1 inhibitor 公开/授权日：2014-07-22
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