发明申请
US20120022273A1 PROCESS FOR THE PREPARATION OF (POLY) AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN USEFUL FOR THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENT
有权
制备用于抗生素治疗药物的应用的EPIPODOPHYLLOTOXIN的（多）氨基氨基甲酰胺衍生物的方法
- 专利标题： PROCESS FOR THE PREPARATION OF (POLY) AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN USEFUL FOR THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENT
- 专利标题（中）： 制备用于抗生素治疗药物的应用的EPIPODOPHYLLOTOXIN的（多）氨基氨基甲酰胺衍生物的方法
-
申请号： US12733864申请日： 2008-09-23
-
公开(公告)号： US20120022273A1公开(公告)日： 2012-01-26
- 发明人: Yves Guminski , Martial Grousseaud , Thierry Imbert
- 申请人： Yves Guminski , Martial Grousseaud , Thierry Imbert
- 申请人地址： FR BOULOGNE BILLANCOURT
- 专利权人： PIERRE FABRE MEDICAMENT
- 当前专利权人： PIERRE FABRE MEDICAMENT
- 当前专利权人地址： FR BOULOGNE BILLANCOURT
- 优先权： FR0706693 20070925
- 国际申请： PCT/FR2008/051700 WO 20080923
- 主分类号： C07D493/04
- IPC分类号： C07D493/04 ; C07C269/06 ; C07C271/22
摘要：
The present invention relates to a new process for the preparation of (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin and salts thereof, characterised in that it comprises a step of peptide coupling of 4-amino-4′-demethylepipodophyllotoxin with an amine-containing reactant having protecting groups.
公开/授权文献
信息查询
