An absorbent article is provided with a waist-cuff to prevent body waste from leaking beyond a waist-opening. An elastic sheet is used for the waist-cuff to be held in contact with the wearer's skin even if the wearer moves. The waist-cuff and a chassis may be joined to each other so as to be separated from each other in the vicinity of an absorbent structure to assure that fitness of the waist-cuff to the wearer's skin is not significantly affected by movement of the wearer and, at the same time, to assure that leg-cuffs can rise without being collapsed by the waist-cuff. The ends of the leg-cuffs are interleaved between the waist-cuff and the chassis to prevent body waste from leaking through a clearance which would otherwise be defined between the leg-cuffs and the waist-cuff.